Химия

One of the widely used antibiotics of the penicillin series in medicine are amoxicillin and amoxiclav – the representatives of "protected" penicillins. To control the concentration of these antibiotics, HPLC, spectrophotometry, capillary electrophoresis are applicable, which are long-lasting, require expensive equipment, operators and are not applicable for the express determination of aminopenicillins in biological and medicinal aqueous.

The article presents the results of quantum chemical calculation of reactivity indices of nine substituted chromenopyrazoles that can be potentially used as ligands for light emitting complex compounds. The molecules chosen for our study contain several potential complexation centers (nitrogen atoms of pyrazol ring and oxygen atoms of chromene fragment) as well as additional chromophoric groups capable of facilitating the excitation energy transfer from ligand to central ion.