Известия Саратовского университета. Новая серия.

Серия Химия. Биология. Экология

ISSN 1816-9775 (Print)
ISSN 2541-8971 (Online)


Для цитирования:

Егунова О. Р., Константинова Т. А., Штыков С. Н. МАГНИТНЫЕ НАНОЧАСТИЦЫ МАГНЕТИТА В РАЗДЕЛЕНИИ И КОНЦЕНТРИРОВАНИИ // Известия Саратовского университета. Новая серия. Серия: Химия. Биология. Экология. 2014. Т. 14, вып. 4. С. 27-35. DOI: 10.18500/1816-9775-2014-14-4-27-35

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русский
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Тип статьи: 
Научная статья
УДК: 
543.054

МАГНИТНЫЕ НАНОЧАСТИЦЫ МАГНЕТИТА В РАЗДЕЛЕНИИ И КОНЦЕНТРИРОВАНИИ

Авторы: 
Егунова Ольга Романовна, Саратовский национальный исследовательский государственный университет имени Н. Г. Чернышевского
Константинова Татьяна Александровна, Саратовский национальный исследовательский государственный университет имени Н. Г. Чернышевского
Штыков Сергей Николаевич, Саратовский национальный исследовательский государственный университет имени Н. Г. Чернышевского
Аннотация: 

Кратко рассмотрены методы получения и функционализации
поверхности магнитных наночастиц на основе магнетита, их
свойства и применение для разделения и концентрирования
неорганических и органических веществ.
 

Список источников: 

1. Губин С. П., Кокшаров Ю. А., Хомутов Г. Б., Юр-
ков Г. Ю. Магнитные наночастицы : методы полу-
чения, строение и свойства // Успехи химии. 2005.
Т. 74, № 6. С. 539–574.
2. Елисеев А. А., Лукашин А. В. Функциональные на-
номатериалы / под ред. Ю. Д. Третьякова. М. : ФИЗ-
МАТЛИТ, 2010. 456 с.
3. Сергеев Г. Б. Нанохимия : учеб. пособие. М. : КДУ,
2007. 336 с.
4. Кособудский И. Д., Симаков В. В., Ушаков Н. М.,
Юрков Г. Ю. Физическая химия наноразмерных объ-

ектов : композиционные материалы. Саратов : Сарат.
техн. ун-т, 2008. 230 с.
5. Hyeon T. Chemical synthesis of magnetic nanoparticles
// Chem. Comm. 2003. № 8. P. 927–934.
6. Gao J., Gu H., Xu B. Multifunctional Magnetic Nanoparticles:
Design, Synthesis, and Biomedical Applications
// Acc. Chem. Res. 2009. Vol. 42, № 8. P. 1097–1107.
7. Veiseh O., Gunn J. W., Zhang M. Design and fabrication
of magnetic nanoparticles for targeted drug delivery
and imaging // Adv. Drug. Deliv. Rev. 2010. Vol. 62.
P. 284–304.
8. Wilhelm C., Gazeau F. Universal cell labelling with
anionic magnetic nanoparticles // Biomaterials. 2008.
Vol. 29. P. 3161–3174.
9. Sandhu A., Handa H., Abe M. Synthesis and applications
of magnetic nanoparticles for biorecognition and point
of care medical diagnostics // Nanotechnology. 2010.
Vol. 21. P. 442001 (22 p.).
10. Mornet S., Vasseur S., Grasset F., Duguet E. Magnetic
nanoparticle design for medical diagnosis and therapy //
J. Mater. Chem. 2004. Vol. 14. P. 2161–2175.
11. Ambashta R. D., Sillanpaa M. Water purification using
magnetic assistance : A review // J. Hazard. Mater. 2010.
Vol. 180. P. 38–49.
12. Giakisikli G., Anthemidis A. N. Magnetic materials as
sorbents for metal/metalloid preconcentration and/or
separation. A review // Anal. Chim. Acta. 2013. Vol. 789.
P. 1–16.
13. Massart R. Preparation of aqueous magnetic liquids in
alkaline and acidic media // IEEE Trans. Magn. 1981.
Vol. 17, № 2. P. 1247–1248.
14. Martinez-Mera I., Espinoza-Pesqueira M.E., PerezHernandez
R., Arenas-Alatorre J. Synthesis of magnetite
(Fe3O4) nanoparticles without surfactants at room
temperature // Mater. Lett. 2007. Vol. 61. P. 4447–4451.
15. Pang S. C., Chin S. F., Anderson M. A. Redox Equilibria
of iron oxides in aqueous – based magnetite dispersions:
Effect of the pH and redox potential // J. Colloid Interface
Sci. 2007. Vol. 311. P. 94–101.
16. Pileni M. P. The Role of soft colloidal templates in controlling
the size and shape of inorganic nanocrystals //
Nature Mater. 2003. Vol. 2. P. 145–150.
17. Pileni M. P. Magnetic Fluids: Fabrication, Magnetic
Properties, and Organization of Nanocrystals // Adv.
Funct. Mater. 2001. Vol. 11, № 5. P. 323–336.
18. Герман С. В., Иноземцева О. А., Маркин А. В., Метвал-
ли Х., Хомутов Г. Б., Горин Д. А. Синтез гидрозолей
магнетита в инертной атмосфере // Коллоид. журн.
2013. Т. 75, № 4. С. 534–537.
19. Mello Donega C., Liljeroth P., Vanmaekelbergh D. Physicochemical
Evaluation of the Hot–Injection Method, a
Synthesis Route for Monodisperse Nanocrystals // Small.
2005. Vol. 1, № 12. P. 1152–1162.
20. Couto G. G., Klein J. J., Schreiner W. H., Mosca D. H.,
Oliveira A. J. A., Zarbin A. J. G. Nickel nanoparticles
obtained by a modifi ed polyol process: synthesis, characterization,
and magnetic properties // J. Colloid Interface
Sci. 2007. Vol. 311. P. 461–468.
21. Park J., An K., Hwang Y., Park J.-G., Noh H.-J.,
Kim J.-Y., Park J.-H., Hwang N.-M., Hyeon T. Ultra–
large–scale syntheses of monodisperse nanocrystals //
Nature Mater. 2004. Vol. 3. P. 891–895.
22. Yu W. W., Falkner J. C., Yavuz C. T., Colvin V. L. Synthesis
of monodisperse iron oxide nanocrystals by thermal
decomposition of iron carboxylate salts // Chem. Comm.
2004. P. 2306–2307.
23. Бычкова А. В., Сорокина О. Н., Розенфельд М. А., Ко-
варский А. Л. Многофункциональные биосовмести-
мые покрытия на магнитных наночастицах // Успехи
химии. 2012. Т. 81, № 11. С. 1026–1050.
24. Xie L., Jiang R., Zhu F., Liu H., Ouyang G. Application of
functionalized magnetic nanoparticles in sample preparation
// Anal. Bioanal. Chem. 2014. Vol. 406. P. 377–399.
25. Dios de A.S., Diaz-Garcia M.E. Multifunctional nanoparticles:
Analytical prospects // Anal. Chim. Acta. 2010.
Vol. 666. P. 1–22.
26. Thanh N. T. K., Green L. A. W. Functionalisation of
nanoparticles for biomedical applications // Nano Today.
2010. Vol. 5. P. 213–230.
27. R?os A., Zougagh M., Bouri M. Magnetic (nano)materials
as an useful tool for sample preparation in analytical
methods. A review // Anal. Methods. 2013. Vol. 15.
P. 23–32.
28. Gupta A. K., Naregalkar R. R., Vaidua V. D., Gupta M.
Recent advances on surface engineering of marnetic iron
oxide nanoparticles and their biomedical applications //
Nanomedicine. 2007. Vol. 2, № 1. P. 23–39.
29. Chen L., Wang T., Tong J. Application of derivatized
magnetic materials to the separation and the preconcentration
of pollutants in water samples // Trends Anal.
Chem. 2011. Vol. 30, № 7. P. 1095–1108.
30. Aguilar-Arteaga K., Rodriguez J. A., Barrado E. Magnetic
solids in analytical chemistry : A review // Anal.
Chim. Acta. 2010. Vol. 674. P. 157–165.
31. Tataj P., Gonzalez-Carreno T., Cerna C. J. Single-step
nanoengineering of silica coated maghemite hollow
spheres with tunable magnetic properties // Adv. Mater.
2001. Vol. 13. P. 1620–1624.
32. Santra S., Tapec R., Theodoropoulou N. Dobson J.,
Hebard A., Tan W. Synthesis and characterization of
silica-coated iron oxide nanoparticles in microemulsion :
the effect of nonionic surfactants // Langmuir. 2001.
Vol. 17. P. 2900–2906.
33. Sadjadi M. S., Fathi F., Farhadyar N., Zare K. Synthesis
and characterization of multifunctional silica coated magnetic
nanoparticles using polyvinylpyrrolidone (PVP) as
a mediator // J. Nano Res. 2011. Vol. 16. P. 43–48.
34. Zhao X., Shi Y., Wang T., Cai Y., Jiang G. Preparation
of silica-magnetite nanoparticle mixed hemimicelle
sorbents for extraction of several typical phenolic compounds
from environmental water samples // J. Chromatogr.
A. 2008. Vol. 1188. P. 140–147.
35. Deng Y., Deng C., Yang D., Wang C., Fu S., Zhang X.
Preparation, characterization and application of magnetic
silica nanoparticle functionalized multi-walled carbon
nanotubes // Chem. Comm. 2005. № 44. P. 5548–5550.

36. Zhang Y., Xu S., Luo Y., Pan S., Ding H., Li G. Synthesis
of mesoporous carbon capsules encapsulated with magnetite
nanoparticles and their application in wastewater
treatment // J. Mater. Chem. 2011. Vol. 21. P. 3664–3671.
37. Ansell R. J., Mosbach K. Magnetic molecularly imprinted
polymer beads for drug radioligand binding assay //
Analyst. 1998. Vol. 123. P. 1611–1616.
38. Wu Y., Zuo F., Zheng Z., Ding X., Peng Y. A Novel Approach
to Molecular Recognition Surface of Magnetic
Nanoparticles Based on Host-Guest Effect // Nanoscale
Res. Lett. 2009. Vol. 4. P. 738–747.
39. Erdem A., Sayar F., Karadeniz H., Guven G., Ozsoz M.,
Piskin E. Development of Streptavidin Carrying Magnetic
Nanoparticles and Their Applications in Electrochemical
Nucleic Acid Sensor Systems // Electroanalysis.
2007. Vol. 19. P. 798–804 .
40. Li J., Wei X., Yuan Y. Synthesis of magnetic nanoparticles
composed by Prussian blue and glucose oxidase for preparing
highly sensitive and selective glucose biosensor //
Sensors Actuators B. 2009. Vol. 139. P. 400–406.
41. Liu Z., Liu Y., Yang H., Yang Y., Shen G., Yu R. A phenol
biosensor based on immobilizing tyrosinase to modifi ed
core – shell magnetic nanoparticles supported at a carbon
paste electrode // Anal. Chim. Acta. 2005. Vol. 533. P. 3–9.
42. Corr S. A., Rakovich Y. P., Gun’ko Y. K. Multifunctional
Magnetic–fl uorescent Nanocomposites for Biomedical
Applications // Nanoscale Res. Lett. 2008. Vol. 3.
P. 87–104.
43. Huang C., Hu B. Silica-coated magnetic nanoparticles
modifi ed with ?-mercaptopropyltrimethoxysilane for fast
and selective solid phase extraction of trace amounts
of Cd, Cu, Hg, and Pb in environmental and biological
samples prior to their determination by inductively
coupled plasma mass spectrometry // Spectrochimica
Acta Part B. 2008. Vol. 63. P. 437–444.
44. Huang C. Z., Xie W., Li X., Zhang J. P. Speciation of
inorganic arsenic in environmental waters using magnetic
solid phase extraction and preconcentration followed by
ICP-MS // Microchim Acta. 2011. Vol. 173. P. 165–172.
45. Suleiman J. S., Hu B., Peng H. Separation/preconcentration
of trace amounts of Cr, Cu and Pb in environmental
samples by magnetic solid-phase extraction with
Bismuthiol-II-immobilized magnetic nanoparticles
and their determination by ICP-OES // Talanta. 2009.
Vol. 77. P. 1579–1583.
46. Zhai Y. H., He Q., Han Q., Duan S.E. Solid-phase extraction
of trace metal ions with magnetic nanoparticles
modifi ed with 2,6-diaminopyridine // Microchim Acta.
2012. Vol. 178. P. 305–412.
47. Li J., Zhao X., Shi Y., Cai Y., Mou S., Jiang G. Mixed
hemimicelles solid-phase extraction based on cetyltrimethylammonium
bromide-coated nano-magnets Fe3O4
for the determination of chlorophenols in environmental
water samples coupled with liquid chromatography/
spectrophotometry detection // J. Chromatogr. A. 2008.
Vol. 1180. P. 24–31.
48. Zhao X., Shi Y., Wang T., Cai Y., Jiang G. Preparation
of silica-magnetite nanoparticle mixed hemimicelle
sorbents for extraction of several typical phenolic compounds
from environmental water samples // J. Chromatogr.
A. 2008. Vol. 1188. P. 140–147.
49. Bagheri H., Zandi O., Aghakhani A. Reprint of: Extraction
of fl uoxetine from aquatic and urine samples using
sodium dodecyl sulfate-coated iron oxide magnetic
nanoparticles followed by spectrofl uorimetric determination
// Anal. Chim. Acta. 2012. Vol. 716. P. 61–65.
50. He Z. Y., Liu D. H., Li R. H., Zhou Z. Q., Wang P.
Magnetic solid-phase extraction of sulfonylurea herbicides
in environmental water samples by Fe3O4@dioctadecyl
dimethyl ammonium chloride@silica magnetic
particles // Anal. Chim. Acta. 2012. Vol. 747. P. 29–35.
51. Sun L., Zhang G., Chen L., Liu J., Jin H., Xu H., Ding L.
Preparation of alumina-coated magnetite nanoparticle
for extraction of trimethoprim from environmental water
samples based on mixed hemimicelles solid-phase extraction
// Anal. Chim. Acta. 2009. Vol. 638. P. 162–168.
52. Liu X. Q., Xing J. M., Guan Y. P., Shan G. B., Liu H. Z.
Synthesis of amino-silane modified superparamagnetic
silica supports and their use for protein immobilization
// Colloids and Surfaces A : Physicochem. Eng.
Aspects. 2004. Vol. 238. P. 127–131.
53. Hiergeist R., Andra W., Buske N., Hergt R., Hilger I.,
Richter U., Kaiser W. Application of magnetite ferro-
fl uids for hyperthermia // J. Magn. Magn. Mater. 1999.
Vol. 201. P. 420–422.
54. Astalan A. P., Ahrentorp F., Johansson C., Larsson K.,
Krozer A. Biomolecular reactions studied using changes
in brownian rotation dynamics of magnetic particles //
Biosensors Bioelectron. 2004. Vol. 19. P. 945–951.
55. Safarik I., Safarikova M. Use of magnetic techniques for
the isolation of cells // J. Chromatogr. B. Biomed. Sci.
Appl. 1999. Vol. 722. P. 33–53.
56. Bucak S., Jones D. A., Laibinis P. E., Hatton T. A. Protein
Separations Using Colloidal Magnetic Nanoparticles //
Biotechnol. Prog. 2003. Vol. 19. P. 477?484.
57. Ma Z., Guan Y., Liu H. Superparamagnetic silica nanoparticles
with immobilized metal affinity ligands for protein
adsorption // J. Magn. Magn. Mater. 2006. Vol. 301.
P. 469–477.
58. Horak D., Ritttich B., Safa J., Spanova A., Lenfeld J.,
Benes M. J. Properties of RNase an immobilized on magnetic
poly(2-hydroxyethyl methacrylate) microspheres //
Biotechnol. Progr. 2001. Vol. 17. P. 447–452.
59. Boom R., Sol C. J. A., Salimans M. M. M., Jansen C. L.,
Van Dillen P. M. E., Van Der Noordaa J. Rapid and
simple method for purifi cation of nucleic acids // J. Clin.
Microbiol. 1990. Vol. 28. P. 495–503.
60. Elaissari A., Holt L., Meunier F., Voisset C., Pichot C.,
Mandrand B., Mabilat C. Hydrophilic and cationic latex
particles for the specifi c extraction of nucleic acids // J.
Biomater. Sci. Polym. 1999. Vol. 10. P. 403–420.
61. Pinto A. D., Forte V. T., Guastadisegni M. C., Martino C.,
Schena F. P., Tantillo G. A comparison of DNA extraction
methods for food analyses // Food. Control. 2007.
Vol. 18. P. 76–80.
62. Ugelstad J., Prestivik W.S., Stenstad P., Kilaas L.,
Kvalheim G. Selective cell separation with monosized
magnetizable polymer beads // Magnetism in Medicine : 

A Handbook / ed. A. Nowak. 1998. Wiley ; N.Y. ; Berlin.
P. 471.
63. Fang C., Zhang M. Multifunctional magnetic nanoparticles
for medical imaging applications // J. Mater.
Chem. 2009. Vol. 19. P. 6258–6266.
64. Zablotskaya A., Segal I., Lukevics E., Maiorov M.,
Zablotsky D., Blums E., Shestakova I., Domracheva I.
Water-soluble magnetic nanoparticles with biologically
active stabilizers // J. Magn. Magn. Mat. 2009. Vol. 321.
P. 1428–1432.
65. Kost J., Wolfrum J., Langer R. Magnetically enhanced
insulin release in diabetic rats // J. Biom. Mat. Res. 1987.
Vol. 21. P. 1367–1373.
66. Paoli V. M., Lacerda S. H. P., Spinu L., Ingber B., Rosenzweig
Z., Rosenzweig N. Effect of an oscillating magnetic
fi eld on the release properties of magnetic collagen
gels // Langmuir. 2006. Vol. 22. P. 5894–5899.
67. Luderer A. A., Borrelli N. F., Panzarino J. N., Mans-
fi eld G. R., Hess D. M., Brown J. L., Barnett E. H.
Glass-ceramic-mediated, magnetic fi eld- induced localized
hyperthermia: response of a murine mammary
carcinoma // Radiat. Res. 1993. Vol. 94. P. 190–198.
68. Mouaziz H., Veyret R., Theretz A., Ginot F., Elaissari A.
Aminodextran containing magnetite nanoparticles
for molecular biology applications: preparation and
evaluation // J. Biomed. Nanotechnol. 2009. Vol. 5.
P. 1–10.
69. Liu T. Y., Hu S. H., Liu K. H., Liu D. M., Chen S. Y. Study
on controlled drug permeation of magnetic-sensitive ferrogels:
effect of Fe3O4 and PVA // J. Control. Release.
2008. Vol. 126. P. 228–236.
70. Chan D. C. F., Kirpotin D. B., Bunn P. A. Synthesis and
evaluation of colloidal magnetic iron oxides for the
site specific radiofrequency-induced hyperthermia
of cancer // J. Magn. Magn. Mater. 1993. Vol. 122.
P. 374–378.
71. Jin H., Kang K. A. Application of novel metal nanoparticles
as optical/thermal agents in optical mammography
and hyperthermic treatment for breast cancer // Adv. Exp.
Med. Biol. 2007. Vol. 599. P. 45–52.
72. Medeirosa S. F., Santos A. M., Fessi H., Elaissari A.
Stimuli-responsive magnetic particles for biomedical
applications // Intern. J. Pharmaceut. 2011. Vol. 403.
P. 139–161.