Izvestiya of Saratov University.

Chemistry. Biology. Ecology

ISSN 1816-9775 (Print)
ISSN 2541-8971 (Online)

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Fluorimetric Determination of Pefloxacin in Pharmaceutical Preparation

Smirnova Tatiana D., Saratov State University
Zhelobitskaya Elena Alexandrovna, Saratov State University
Danilina Tatiana Grigorievna, Saratov State University

It is shown that pefloxacin forms a terbium complexes in neutral and mildly acidic conditions which are characterized by energy transfer. It is found that the micellar surfactant medium energy transfer efficiency increases. The maximum increase sensitized fluorescence intensity is observed in the presence of SDS micelles. A fluorimetric method for determination of pefloxacin in the drug was developed.


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