Izvestiya of Saratov University.

Chemistry. Biology. Ecology

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ISSN 2541-8971 (Online)

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Assessment of the Impact of the Nanoparticles of Silver Stabilized by Polymeric Compounds on Survival of Strains of Staphylococcus aureus

Shulgina Tatiana A., Saratov State Medical University
Glinskaya Elena V., Saratov State University
Nechayeva O V, Saratov State Medical University
Torgashova Anna S., Saratov State Medical University
Zubova Ksenia V., Saratov State University

The antimicrobial activity of the nanoparticles of silver stabilized by various natural and synthetic polymeric compounds concerning reference and clinical strains of Staphylococcus aureus is studied. It is established that the greatest effectiveness was displayed by the silver nanoparticles stabilized by polyvinyl alcohol, carboxymethylcellulose and poliazolidinammonium, the modified iodine hydrate ions. The low sensitivity of the studied strains to action of the nanoparticles stabilized by an oleate of S. aureus sodium probably is connected by its low stabilizing ability and high speed of aggregation of nanoparticles. The high level of toxicity of dodecyl sulphate sodium led to an increase in its antimicrobial activity. The conducted researches allowed us to establish that the most effective antimicrobial components when developing antiseptic and disinfectants are the silver nanoparticles stabilized poliazolidinammonium, modified iodine hydrate ions.

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