Based on the identification and characteristics of the response of aquatic plants to spav-containing drugs, the potential danger of possible contamination of the aquatic environment with spav was assessed. The extent of damage from the effects of spavcontaining drugs on aquatic plants was determined using aquatic plants Elodea сanadensis Michx.(1802), Potamogeton perfoliatus L. (1753), Myriophyllum spicatum L. (1753), Najas minor All. (1773) and Lemna minor L. (1753). As a result of the experiment, the biological effects on the studied plants by different concentrations of spav-containing drugs (dishwashing agents FAIRY and Sanfor Activ) using concentrations of spav-containing drug were revealed 0.3, 0.5, 0.75, 1.0, 2.0, 3.0 and 4.0 ml/l of spav-containing drug was monitored for plant reaction for several weeks. It was found that for the studied aquatic plants, the common registered consequences were: leaf depigmentation; fall of depigmented and non-depigmented leaves and a decrease in plant biomass. The total amount of SMS-means that did not lead to visible changes in model systems with Elodea vanadensis and Najas minor was more than three times higher than in experiments with Potamogeton perfoliatus and Myriophyllum spicatum. The location of macrophytes in the series of increasing resistance to synthetic surfactants from less stable Potamogeton perfoliatus to more stable Elodea canadensis is shown. This order of arrangement of macrophytes in the series of increasing stability is confirmed by experimental results. The revealed tendency of increase of stability of macrophytes has practical value in the selection of the most suitable species of plants for development of ecological technologies for the improvement of the quality of water.