oral fluid

Solid-state Potentiometric Sensors for the Determination of Cefuroxime Axetil in Aqueous Media and Oral Fluid

Cefuroxime axetil is a cephalosporin antibiotic of the second generation, it is used in the sequential therapy of patient with sinusitis, community-acquired pneumonia, and other infectious somatic pathologies. For the determination of cephalosporin antibiotics in different objects, spectroscopic, chromatographic, electrochemical methods, immunoassay, etc. are used, which demand for expen- sive devices and organic solvents. Potentiometric sensors let one expressively detect cefalosporin antibiotics in small samples without previous sample preparation.