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Possibility and perspectives of the complex approach to environment quality estimation are shown in this article for the different types of aquatic ecosystems on base of the midge larvae using. The advantage and defect of the investigations on different levels of its organization (community (taxocenosis), populations, individuals, cells and molecular fevel) are demonstrated. 

| was suggested to contain in ecological scales of L.G. Ramenskiy et al. (1957) additionally 57 new species on the basis of 593 phytocoenological vegetation characteristics in Saratov region. |п this paper the list of additional species and their ecological formulas are considered. 

The results of studying the reactivity of carbonyl-substituted hydroxycyclohexanones with nitrogen-containing polynucleophilic reagents of aromatic, aliphatic, and alicyclic series are summarized. Products of amination by the most active alicyclic carbonylic group of either one or two substrate molecules, enamine products or producis of heterocyclization are shown to be formed, depending on the aminating reagent nature and reaction conditions.

The antiphage and antioxidant activity of a substituted coumarin series and synthesized complicated-built triketones, based on 4-hydroxycoumarin, are investigated, Strucfure-property relationship, the influence of the planarity of molecules on the T4 bacteriophage — culture ES Colli В is revealed; an opportunity of use of oxycoumarins as medium of stabilization of dried samples of vaccinal culture У Pestis EV NII EG.

Synthetic pathways for substituted decahydroacrydine-1,8-diones in the reaction of amination of methylene-(arylidene-, 5-R-2-furfurylidene)-bis-cyclohexane-1,3-diones and by means of condensation of cyclic enaminoketones with aldehydes of various classes were found. Peculiarities of oxymation and reduction of decahydroacrydine-1,8- diones related to the nature of the C9 substituent in the heteroring were revealed. With the aid of Fischer reaction, hexahydrobisindolo[2,3-a:3',2'-j] acrydines were obtained for the first time.

Reactions of carbonyl-containing spirohydro(pyrane)chromans, -furans with hydrogen sulfide and acids are summarized. Depending on the substrate structure and reaction conditions, either complex-structure heterobridge compounds with the spirofragment carbonylic group involved, or the heterocycle is recycled in the case of condensed spirohydropyranes. For spirohydrofurans, recyclization is hindered and thionation of the carbonylic group of the condensed alicycle is observed at reactions with hydrogen sulfide.

Own research results of the structure and heterocyclizations of the alkylarylsubstituted 2,4-dichloro-2-pentene- and 2,4-dichloropentane-1,5-diones were summarized. Dichlorosubstituted pentenedi-ones and there saturated analogs turn out different transformations in the reactions with the same reagents have been founded.

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