amoxicillin

The method has been proposed for the spectrophotometric determination of antibiotics of the cephalosporin (cefuroxime, ceftriaxone, cefotaxime, cefazolin) and penicillin (amoxicillin) groups using chemometric data processing (method of partial least squares, PLS). The absorption spectra of 24 binary mixtures of “cephalosporin – cephalosporin” and 16 binary mixtures of “cephalosporin – amoxicillin” with various concentrations in the range of 3–27 and 5–140 μg/ml have been recorded.

The transport processes occurring in polymer matrix characterize their physico-chemical properties, determine the directions of practical application. The literature data on ion transport in plasticized polymer membranes and theoretical aspects of membrane transport are critically reviewed. The eff ect of the modifi er on the transport properties of membranes is shown.

One of the widely used antibiotics of the penicillin series in medicine are amoxicillin and amoxiclav – the representatives of "protected" penicillins. To control the concentration of these antibiotics, HPLC, spectrophotometry, capillary electrophoresis are applicable, which are long-lasting, require expensive equipment, operators and are not applicable for the express determination of aminopenicillins in biological and medicinal aqueous.

One of the widely used antibiotics of the penicillin series in medicine are amoxicillin and amoxiclav – the representatives of "protected" penicillins. To control the concentration of these antibiotics, HPLC, spectrophotometry, capillary electrophoresis are applicable, which are long-lasting, require expensive equipment, operators and are not applicable for the express determination of aminopenicillins in biological and medicinal aqueous.