антибактериальная фотодинамическая терапия

 This study examined the eff ectiveness of antimicrobial photodynamic therapy (APDT) in the treatment of simulated purulent abdominal abscesses in laboratory animals. Two “radiation + photosensitizer” regimens were tested: 1) using red LED (660 nm) radiation and methylene blue, 2) using laser infrared (808 nm) radiation and indocyanine green.

This study evaluated the effi cacy of transcutaneous photodynamic therapy using blue (428 nm) LED irradiation on Staphylococcus aureus 11 in combination with a water-soluble cationic pyridyl porphyrin and optical clearing agents (OCA) in an ex vivo model. Results showed that OCA signifi cantly enhanced photodynamic inactivation with a 61% reduction in bacterial cell counts after 15 minutes of light exposure, comparable to direct irradiation.