Izvestiya of Saratov University.

Chemistry. Biology. Ecology

ISSN 1816-9775 (Print)
ISSN 2541-8971 (Online)


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(downloads: 111)
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Russian
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Article type: 
Article
UDC: 
504.75

Study of Correlation between Growth Rate of Children and Monophtalate Concentrations in Urine

Autors: 
Zaitseva N. V., Perm State University
Ulanova T. S., Federal Scientific Center for Medical and Preventive Health Risk Management Technologies
Karnazhitskaya T. D., Federal Scientific Center for Medical and Preventive Health Risk Management Technologies
Zavernenkova E. O., Federal Scientific Center for Medical and Preventive Health Risk Management Technologies
Abstract: 

The study presents the results of determining of phthalate metabolites in urine of pre-school and primary school children by HPLC/MS. The correlation between growth rate of children and the concentration of phthalate metabolites in their urine was examined. The detected range of phthalate metabolite concentrations (mono-methyl phthalate, mono-butyl phthalate, mono-ethylhexyl phthalate) in urine of children was 0.0004–0.012 mg/dm3. The analysis of dependencies «urinary concentrations of phthalate metabolites and children growth rate» has revealed statistically significant inversely proportional dependence of the growth rate of the 7 years old boys on the urinary concentration of mono-methyl phthalate (R2=0.38; р<0.05).

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