Izvestiya of Saratov University.
ISSN 1816-9775 (Print)
ISSN 2541-8971 (Online)

SERS-active electrodes

Electrochemical SERS study of some endogenous components of human biofl uids

The work describes electrochemical (EC) protocol suitable for preparation of copper electrodes which can be used as substrates in surface-enhanced Raman spectroscopy (SERS). These SERS-active electrodes have been used for electrospectral studies based on the combination of electrochemical and SERS analysis (EC-SRS analysis). Several endogenous bodyfl uid components (urea, creatinine, uric acid, bilirubin) have been selected for the study because they can signifi cantly aff ect the SERS-based determination of other analytes in bodyfl uids (for example, drugs).