Izvestiya of Saratov University.
ISSN 1816-9775 (Print)
ISSN 2541-8971 (Online)


амидокислота

Interaction of Maleic Anhydride with 1,2-phenylenediamine under Different Conditions

The reaction of maleic anhydride with 1,2-phenylenediamine when heated in an aprotic solvent, regardless of temperature, proceeds with the initial formation of the primary addition product, namely, 4-[(2-aminophenyl)amino)-4-oxobut-2-enoic acid, which further undergoes heterocyclization within two ways, due to the presence of several electrophilic centers in the molecule, depending on the reaction conditions.