Based on the identification and characteristics of the response of aquatic plants to spav-containing drugs, the potential danger of possible contamination of the aquatic environment with spav was assessed. The extent of damage from the effects of spavcontaining drugs on aquatic plants was determined using aquatic plants Elodea сanadensis Michx.(1802), Potamogeton perfoliatus L. (1753), Myriophyllum spicatum L. (1753), Najas minor All. (1773) and Lemna minor L. (1753).