The article describes basic stages of creation and development the Herbarium of Lobachevsky State University of Nizhni Novgorod (NNSU), since the 20-s of the last century, shows the main areas of floristic researches. Designated the current status of the Herbarium. Given a list of the main species of plants described from the territory of the region. The necessity of the search and identification of authentic samples is shown. Results of revision on the type in the in the Herbarium of Lobachevsky State University of Nizhni Novgorod (NNSU) are psesented.