Izvestiya of Saratov University.
ISSN 1816-9775 (Print)
ISSN 2541-8971 (Online)


sound

Changes in Blood-Brain Barrier Permeability under the Influence of Loud Sound

The development of methods of drug delivery to the brain is one of the priorities of the therapy of most cerebral diseases. There are more than 70 technologies to overcome the blood-brain barrier (BBB), but many of them are not widely used in daily clinical practice, as they lead to negative consequences. Here we propose a new method of overcoming the BBB using loud sound (110 dB, 370 Hz, duration – 2 hours).