Izvestiya of Saratov University.
ISSN 1816-9775 (Print)
ISSN 2541-8971 (Online)


scopoletin

Synthesis and biological activity of compounds based on 4-hydroxycoumarin

Currently, the synthesis of oxygen-containing heterocyclic compounds containing a fused benzene ring system with a pyrone cycle, represented by 4-hydroxycoumarin (4-hydroxy-2H-chromen-2-one), is of great importance due to their broad spectrum of biological activity. We found it interesting to conduct reactions of 1,5-dicarbonyl compounds based on 4-hydroxycoumarin with N-nucleophiles, both from a fundamental point of view and from the perspective of the practical application of the resulting products.