Izvestiya of Saratov University.
ISSN 1816-9775 (Print)
ISSN 2541-8971 (Online)

positional isomers

Reaggregation Positional Isomers Tetrazologeksahidroquinazoline

9-phenyl-4,5,6,7,8,9-geksagidrotetrazolo[5,1-b]quinazoline in solution undergoes reaggregation ent via an azide to form a positional isomer corner structure that is installed involving spectral methods (1H-NMR, IR -spectra), TLC, chromato-mass spectrometry.

Synthesis of Opto-R-Phenyl Benzimidazoloheksahydroquinazoline with Angular Articulation Rings

Condensation of 2-aminobenzimidazole, ortho-substituted benzaldehydes and cyclohexanone proceeds with the formation of 10-o-Rsubstituted phenyl benz[4,5]imidazolo-6,7,8,9,10,11-hexahydro[1,2-a] quinazolines having angular articulation rings, strukture which is set using IR, NMR, 1 H, 13C spectra.

Synthesis and Ways of Formation of Hydroxyphenyl Substituted Benz[4,5]imidazole-1,2,3,4,5,6- hexahydro[1,2-a]quinazolines

To synthesize new potentially biologically active benzimidazoloquinazolines, a three-component condensation of 2-aminobenzimidazole, cyclohexanone and hydroxylatedbenzaldehydes was studied. The reaction proceeds regioselectively when the equimolar ratios of the reagents are boiled for 3 hours in N,N-dimethylformamide and is accompanied by the formation of ortho-phenyl substituted hexahydrobenz[4,5]imidazolo [1,2-a]quinazolines having an angular articulation of the rings and a different number and position of hydroxyl groups in the phenyl substituent.

Synthesis and Ways of Formation of Hydroxyphenyl Substituted Triazolohexahydroquinazolines

With three-component condensation of 1,2,4-triazol-3-amine, hydroxy-substituted aromatic aldehyde (2-hydroxybenzaldehyde, 4-hydroxybenzaldehyde, 4-hydroxy-3-methoxybenzaldehyde, 2-naphthalene-carbaldehyde), cyclohexanone, the aldehyde component has a defining impact on the shaping of triazologic hydroquinazolines with different types of rings articulation and the position of the double bond in them (C4a–C5 and C4a–C8a).

One-pot synthesis and structure of isomeric aryl-substituted triazolohexahydroquinazolines

Aryl-substituted triazolohexahydroquinazolines have been synthesized by means of three-component condensation of pnitro(pbromo) benzaldehydes, cyclohexanone, 1,2,4-triazol-3-amine. A scheme of the reaction mechanism is proposed, which makes it possible to explain the features of the behavior of p-nitro(bromo) benzaldehydes in condensation reactions in comparison with their ortho-substituted analogs.