Possibility of Determination of Specific Activity of O-Ag in the Production of Cholera Chemical Vaccine by Dot-Analysis

Cholera remains a global threat to public health. Even sporadic cases of importation of the infection cause significant socio-economic damage. In connection with the current situation, the development and improvement of modern safe chemical vaccines against cholera caused by V. cholerae O1 and O139 serogroups plays an important role in reducing the incidence, which is an important and promising direction of scientific research.