Izvestiya of Saratov University.
ISSN 1816-9775 (Print)
ISSN 2541-8971 (Online)


nitric oxide

Role of Sex Hormones in Regulation of Basal and Stressed Secretion of Nitric Oxide in Normotensive and Hypertensive Rats

We studied effects of gonadectomy on nitric oxide content in blood in normotensive and hypertensive females and males at rest and stress situation. We revealed the stronger estrogens but not androgens in regulation of basal and stressed secretion of nitric oxide under differ­ ent physiological conditions (rest, stress, arterial hypertension) that may be one of possible mechanism responsible for higher cardiovas­ cular resistance to stress-induced damages in female compared with male.