Izvestiya of Saratov University.
ISSN 1816-9775 (Print)
ISSN 2541-8971 (Online)


cephalexin

Determination of the Main Substances in the Preparations of Cephalexin and Cefuroxime Axetil

Techniques of determination of the main substances in capsules of cephalexin and tablets of cefuroxime axetil have been elaborated. For separation of ancillary compounds, the two modes have been approbated, i.e. filtration and centrifugation. The advantage of the second means has been shown.

Express determination of cephalexin

Test means based on immobilized Fehling’s reagent for the determination of cephalexin have been obtained. Methods for visual and colorimetric assessment of antibiotic concentration using a smartphone camera have been developed. The optimal conditions for the indicator reaction have been selected with varying heating time and temperature. For a visual semi-quantitative assessment of the content of cephalexin, a color scale has been obtained.