biological activity

The biological activity of chitosan oligomers of various molecular masses was examined on E.coli (АТСС 25922), S.aureus (АТСС 25923), and fungus Candida albicans (АТСС 10231). All the samples under study inhibited the growth of these microorganisms, especially S.aureus. The dependence of the biological activity of chitosan oligomers on their concentration, exposure time, and molecular mass has been established.

The results of the research in the field of studying the relationship of the geometric structure of organic compounds with their biological activity are presented. It has been shown that the stereospecific structure of organic and inorganic molecules can have a direct effect on the biologically active properties of substances. Among the known types of stereoisomerism (geometric and optical), this work summarizes the effect of various types of geometric isomerism on the bioactivity of compounds. In addition, the results of the authors’ own research are presented.