Izvestiya of Saratov University.
ISSN 1816-9775 (Print)
ISSN 2541-8971 (Online)


лекарственные препараты

Smartphone use in solid-phase fl uorimetric determination of some polypeptide antibiotics in medicinal preparations

The analysis of semi-products at diff erent stages of production and fi nished medicinal products is an integral part of an eff ective quality assurance system for pharmaceutical production. The traditional methods used in the pharmaceutical fi eld, such as capillary electrophoresis, gas and liquid chromatography, are quite versatile and eff ective. However, they are distinguished by the high cost of instrumentation and component materials, the need to use high-purity solvents, the lack of mobility and the possibility of in situ studies.

Determination of the Main Substances in the Preparations of Cephalexin and Cefuroxime Axetil

Techniques of determination of the main substances in capsules of cephalexin and tablets of cefuroxime axetil have been elaborated. For separation of ancillary compounds, the two modes have been approbated, i.e. filtration and centrifugation. The advantage of the second means has been shown.

Research of a State of Some the Cephalosporin Antibiotics in Water Environments by Spectrophotometry

An express authenticity estimation of some cephalosporin antibiotics of II and III generations are developed by spectrophotometry. An identity of drugs such as cefotaxime (Russia) and claforan (France), cefuroxime (Russia) and cefuroxime axetil (England) is shown.