Cite this article as:

Sindeev S. S., Zinchenko E. M., Ulanova M. V., Gekalyuk A. S., Agranovich I. M., Semyachkina-Glushkovskaya O. V., Kassim M. ., Sindeeva O. A. The Effect of Emotional and Severe Pathological Stresses on the Level of Arterial Pressure and the Production of Testosterone in Female and Male Rats. Izvestiya of Saratov University. New series. Series: Chemistry. Biology. Ecology, 2015, vol. 15, iss. 2, pp. 46-53.


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UDC: 
612.143
Language: 
Russian

The Effect of Emotional and Severe Pathological Stresses on the Level of Arterial Pressure and the Production of Testosterone in Female and Male Rats

Abstract

The serum level of testosterone is indicator of organismcapacity. Chronic stress is accompanied by development of more pronounced arterial hypertension in males compared with females that is associated with the decrease in production of testosterone in males but not in females. Severe stress causes hemorrhagic stroke in hypertensive animals, accompanied by a significant change in the level of blood pressure in males than in females (pressure responses during stress and hypotensive reactions after stress) and more significant decrease in secretion of testosterone in males in compared with females. Our results improve our knowledgeabout the role of androgens in cardiovascular stress-resistance and mechanisms of adaptation to stress in the male and female organism as well as its have practical importance, being «quantitative» indicators of adaptive organism capacity.

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