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Smirnova T. D., Zhelobitskaya E. A., Danilina T. G. Fluorimetric Determination of Pefloxacin in Pharmaceutical Preparation. Izvestiya of Saratov University. Chemistry. Biology. Ecology, 2016, vol. 16, iss. 4, pp. 372-376. DOI:

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Fluorimetric Determination of Pefloxacin in Pharmaceutical Preparation


It is shown that pefloxacin forms a terbium complexes in neutral and mildly acidic conditions which are characterized by energy transfer. It is found that the micellar surfactant medium energy transfer efficiency increases. The maximum increase sensitized fluorescence intensity is observed in the presence of SDS micelles. A fluorimetric method for determination of pefloxacin in the drug was developed.


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