antimicrobial activity

We developed various options of biologically active agents based on the core–shell structure technology. They were obtained by layering biocompatible polymer on the surface of the carriers. As a core, we used a heterocyclic compound comprising of enamine and flavonoid nanoaggregates. As a shell, we used polу azolidinе аmmonium modified by iodine hydrate-ions. Our results implied a significant increase in antimicrobial activity of the preparations developed by us.

The complex estimation of toxicity of the polymer compounds – poly azolidin ammonium, modified hydrate ions of iodine, which has high antimicrobial activity was held. It is established that working concentrations of parent drug and its variants with different hydrate ions of iodine content do not cause death of biotestobjects of Daphnia magna Straus.